Six New 9,19-Cycloartane Triterpenoids from Cimicifuga foetida L.
نویسندگان
چکیده
منابع مشابه
Trinor-cycloartane glycosides from the rhizomes of Cimicifuga foetida.
Three new trinor-cycloartane glycosides, 15alpha-hydroxy-16-dehydroxy-16(24)-en-foetidinol-3-O-beta-D-xylopyranoside (1), 28-hydroxy-foetidinol-3-O-beta-D-xylopyranoside (2) and foetidinol-3-O-beta-D-xylopyranosyl-(1"-->3')-beta-D-xylopyranoside (3) together with the known compound foetidinol-3-O-beta-D-xylopyranoside (4) were isolated from the n-BuOH fraction of the roots of Cimicifuga foetida...
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A new cycloartane bisdesmoside and two new trinorcycloartane glycosides, along with four known cycloartane compounds, were isolated from the rhizomes of Cimicifuga dahurica (Ranunculaceae). The structures of the new compounds were elucidated as 3-O-alpha-L-arabinopyranosyl cimigenol 15-O-beta-D-glucopyranoside, 24-hydroxy-12beta-acetoxy-25,26,27-trinorcycloartan-16,23-dione 3beta-O-alpha-L-arab...
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Three new 15,16-seco-cycloartane glycosides, which were constructed by a C-C bond cleavage in the D ring, have been isolated from Cimicifuga Rhizome for the first time. Their structures were determined by the use of 2D NMR techniques and chemical evidence.
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Two new cycloartane-type triterpene glycosides, namely cimicifoetisides A (1) and B (2), along with seven known compounds cimigenol, 25-O-acetylcimigenol, cimigenol 3-O-beta-D-xylopyranoside, 12beta-hydroxycimigenol 3-O-beta-D-xylopyranoside, cimigenol 3-O-alpha-L-arabinopyranoside, 25-deoxyshengmanol 3-O-beta-D-xylopyranoside and cimilactone A, were isolated from the rhizomes of Cimicifuga foe...
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Phytochemical analysis of A. balsamea oleoresin led to the isolation of three new 3,4-seco-lanostane triterpenoids 1-3, one new cycloartane triterpenoid 4 along with fourteen known terpenoids. Structure determinations were based on extensive 1D/2D NMR, IR and MS spectroscopic analyses, and comparison with literature data. The isolated compounds were evaluated in vitro for their cytotoxicity aga...
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ژورنال
عنوان ژورنال: Natural Products and Bioprospecting
سال: 2016
ISSN: 2192-2195,2192-2209
DOI: 10.1007/s13659-016-0097-3